The GRIA3 Antibody (N-term) from MyBioSource.com is a Rabbit Polyclonal antibody to AMPA, GluA3, and GRIA3. This antibody recognizes Human, Mouse, and Rat antigen. The GRIA3 Antibody (N-term) has been validated for the following applications: ELISA, and Western Blot.
Description
Glutamate receptors are the predominant excitatory
neurotransmitter receptors in the mammalian brain and are activated
in a variety of normal neurophysiologic processes. These receptors
are heteromeric protein complexes composed of multiple subunits,
arranged to form ligand-gated ion channels. The classification of
glutamate receptors is based on their activation by different
pharmacologic agonists. The subunit encoded by this gene belongs to
a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole
propionate)-sensitive glutamate receptors, and is subject to RNA
editing (AGA->GGA; R->G). Alternative splicing at this locus
results in different isoforms, which may vary in their signal
transduction properties